Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Congenital combined deficiency of coagulation factors VII and X--different genetic mechanisms.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 May 2015

Pavlova A, Preisler B, Driesen J, de Moerloose P, Zieger B, Hütker S, Dengler K, Harbrecht U, Oldenburg J

Abstract excerpt

Combined coagulation factor VII (FVII) and factor X (FX) deficiency (combined FVII/FX deficiency) belongs to the group of bleeding disorders in which both factors show reduced plasma activity. It may arise from coincidental inheritance of separate coagulation factor deficiencies or a common cause as large deletions comprising both gene loci. The F7 and F10 genes are located on the long arm of chromosome 13. Here,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation Tests
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 13

Share to Factor VII

Share to Factor VII Deficiency

Share to Factor X

Share to Heterozygote

Share to Pedigree

Source

Identifiers

PMID: 25582404
DOI: 10.1111/hae.12604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Congenital combined deficiency of coagulation factors VII and X--different genetic mechanisms.PMID 25582404Read ↗

Large deletions play a minor but essential role in congenital coagulation factor VII and X deficiencies.Semantic proximity Read ↗

Synergistic effect of factor VII gene polymorphisms causing mild factor VII deficiency in a case of severe factor X deficiency.Semantic proximity Read ↗

Factor X deficiency.Semantic proximity Read ↗

[Phenotype and genotype analysis for a consanguineous pedigree with combined coagulation factor VII and X deficiency].Semantic proximity Read ↗

Factor VII deficiency and the FVII mutation database.Semantic proximity Read ↗

[Gene analysis of a combined inherited factor VII and factor X deficiency pedigree].Semantic proximity Read ↗

Combined coagulation factor VIII and factor IX deficiency (CDF8F9) in a patient from Lithuania.Semantic proximity Read ↗

Combination of congenital coagulation disorders: Factor II gene mutation G20210A, Factor V Leiden gene mutation G1691A and protein S deficiency. a family study.Semantic proximity Read ↗

F7 gene variants modulate protein levels in a large cohort of patients with factor VII deficiency. Results from a genotype-phenotype study.Semantic proximity Read ↗

Identification of a novel factor X deletion in combination with a missense mutation in the F10 gene - Genotype-phenotype correlation in a girl with severe factor X deficiency.Semantic proximity Read ↗

Combined congenital dysfibrinogenemia and factor VII deficiency from mutations in the FGB and F7 genes.Semantic proximity Read ↗

Characterization of combined factor VII and factor XI deficiencies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.