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Article

Synergistic effect of factor VII gene polymorphisms causing mild factor VII deficiency in a case of severe factor X deficiency.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2017

Deshpande Rutuja, Ghosh Kanjaksha, Shetty Shrimati

Abstract excerpt

Congenital combined deficiency of coagulation factors VII and X are mainly attributed to large deletions involving both the genes in chromosome 13 or occasionally due to the coincidental occurrence of independently occurring mutations. We report the molecular basis of congenital combined deficiency of factors VII and X in a 6-year-old female child. Direct DNA sequencing of both factor VII (F7) and factor X (F10)...

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PMID: 26919454
DOI: 10.1097/MBC.0000000000000544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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