Transcriptome analysis of cyclic AMP ‐dependent protein kinase A –regulated genes reveals the production of the novel natural compound fumipyrrole by A spergillus fumigatus

Abstract excerpt

Aspergillus fumigatus is an opportunistic human pathogenic fungus causing life-threatening infections in immunocompromised patients. Adaptation to different habitats and also virulence of the fungus depends on signal perception and transduction by modules such as the cyclic AMP-dependent protein kinase A (PKA) pathway. Here, by transcriptome analysis, 632 differentially regulated genes of this important signaling...

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