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Article

RASSF5A, a candidate tumor suppressor, is epigenetically inactivated in esophageal squamous cell carcinoma.

Clinical & experimental metastasis - 1 Jan 2015

Guo Wei, Wang Cong, Guo Yanli, Shen Supeng, Guo Xin, Kuang Gang, Dong Zhiming

Abstract excerpt

As a result of alternative splicing and differential promoter usage, RASSF5 exists in at least three isoforms (RASSF5A-RASSF5C), which may play different roles in tumorigenesis. The present study was to detect the role of RASSF5A, B and C in esophageal squamous cell carcinoma (ESCC) and clarify the critical CpG sites of RASSF5A, in order to clarify more information on the role of RASSF5 with regard to the...

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Source

Identifiers

PMID: 25579665
DOI: 10.1007/s10585-015-9693-6

Genes

RASSF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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