Article
Quality control of genotypes using heritability estimates of gene content at the marker.
Genetics - 1 Mar 2015
Forneris Natalia S, Legarra Andres, Vitezica Zulma G, Tsuruta Shogo, Aguilar Ignacio, Misztal Ignacy, Cantet Rodolfo J C
Abstract excerpt
Quality control filtering of single-nucleotide polymorphisms (SNPs) is a key step when analyzing genomic data. Here we present a practical method to identify low-quality SNPs, meaning markers whose genotypes are wrongly assigned for a large proportion of individuals, by estimating the heritability of gene content at each marker, where gene content is the number of copies of a particular reference allele in a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.