Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Creating a "Prosurvival Phenotype" Through Histone Deacetylase Inhibition: Past, Present, and Future.

Shock (Augusta, Ga.) - 1 Aug 2015

Halaweish Ihab, Nikolian Vahagn, Georgoff Patrick, Li Yongqing, Alam Hasan B

Abstract excerpt

Traumatic injuries and their sequelae represent a major source of mortality in the United States and globally. Initial treatment for shock, traumatic brain injury, and polytrauma is limited to resuscitation fluids to replace lost volume. To date, there are no treatments with inherent prosurvival...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Injuries
Share to Cytoplasm
Share to Hemorrhage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone Deacetylase Inhibitors

Share to Histone Deacetylases

Share to Protein Processing, Post-Translational

Share to Sepsis

Share to Wounds and Injuries

Source

Open in PubMed Open full text

Identifiers

PMID: 25565645
DOI: 10.1097/SHK.0000000000000319
PMCID: PMC4492909

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25565645-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Creating a "Prosurvival Phenotype" Through Histone Deacetylase Inhibition: Past, Present, and Future.PMID 25565645Read ↗

Creating a pro-survival and anti-inflammatory phenotype by modulation of acetylation in models of hemorrhagic and septic shock.Semantic proximity Read ↗

The Role of Histone Deacetylases in Acute Lung Injury—Friend or FoeSemantic proximity Read ↗

Histone deactylase gene expression profiles are associated with outcomes in blunt trauma patientsSemantic proximity Read ↗

Creating a "pro-survival" phenotype through epigenetic modulation.Semantic proximity Read ↗

Epigenetic Regulation in Ischemic Neuroprotection: The Dual Role of HDACs and HATs in Neuroinflammation and RecoverySemantic proximity Read ↗

Targeting extranuclear histones to alleviate acute and chronic inflammationSemantic proximity Read ↗

Histone Deacetylases Exert Class-Specific Roles in Conditioning the Brain and Heart Against Acute Ischemic InjurySemantic proximity Read ↗

Novel Therapeutic Strategy Targeting Hspa8 for Ischemic Brain InjurySemantic proximity Read ↗

Heat shock proteins: multiple neuroprotective functions and implications for neurologic disease.Semantic proximity Read ↗

Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1α/ASK1/JNK signaling pathway in mice with traumatic brain injurySemantic proximity Read ↗

Mild traumatic brain injury-induced hippocampal gene expressions: The identification of target cellular processes for drug developmentSemantic proximity Read ↗

The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in RecoverySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.