Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Androgen receptor actions modify skin structure and chemical carcinogen-induced skin cancer susceptibility in mice.

Hormones & cancer - 1 Feb 2015

Simanainen Ulla, Ryan Tegan, Li Desmond, Suarez Francia Garces, Gao Yan Ru, Watson Geoff, Wang Yiwei, Handelsman David J

Abstract excerpt

Men are significantly more susceptible to non-melanoma skin cancers than women, and the androgen receptor (AR) is widely distributed in the skin, suggesting a ro\le for androgens acting via AR. Therefore, we explored the role of androgen action via AR in susceptibility to experimental 7,12-dimethylbenz[a]anthracene (DMBA)-induced skin carcinogenesis and in skin structural development of male and female mice. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androgens
Share to Carcinogens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen

Share to Cyclooxygenase 1

Share to Cyclooxygenase 2

Share to Disease Susceptibility

Share to Neoplasms, Experimental

Share to Receptors, Androgen

Source

Open in PubMed Open full text

Identifiers

PMID: 25563841
DOI: 10.1007/s12672-014-0210-1
PMCID: PMC10355911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Androgen receptor actions modify skin structure and chemical carcinogen-induced skin cancer susceptibility in mice.PMID 25563841Read ↗

Androgen resistance in female mice increases susceptibility to DMBA-induced mammary tumors.Semantic proximity Read ↗

Characterization of skin tumor promotion by mirex: structure-activity relationships, sexual dimorphism and presence of Ha-ras mutation.Semantic proximity Read ↗

Chemically induced skin carcinogenesis: Updates in experimental models (Review)Semantic proximity Read ↗

Non-melanoma skin cancer in mouse and man.Semantic proximity Read ↗

Aryl Hydrocarbon Receptor in Keratinocytes Is Essential for Murine Skin Barrier IntegritySemantic proximity Read ↗

The genetic control of chemically and radiation-induced skin tumorigenesis: a study with carcinogenesis-susceptible and carcinogenesis-resistant mice.Semantic proximity Read ↗

Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesisSemantic proximity Read ↗

Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression.Semantic proximity Read ↗

Functions of the aryl hydrocarbon receptor in the skinSemantic proximity Read ↗

Selective ablation of glucocorticoid receptor in mouse keratinocytes increases susceptibility to skin tumorigenesis.Semantic proximity Read ↗

Sex Differences in Photoprotective Responses to 1,25- Dihydroxyvitamin D3 in Mice are Modulated by the Estrogen Receptor-βSemantic proximity Read ↗

Role of androgen and estrogen receptors for the action of dehydroepiandrosterone (DHEA).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.