Article
Influence of culture conditions and extracellular matrix alignment on human mesenchymal stem cells invasion into decellularized engineered tissues.
Journal of tissue engineering and regenerative medicine - 1 May 2015
Weidenhamer Nathan K, Moore Dusty L, Lobo Fluvio L, Klair Nathaniel T, Tranquillo Robert T
Abstract excerpt
The variables that influence the in vitro recellularization potential of decellularized engineered tissues, such as cell culture conditions and scaffold alignment, have yet to be explored. The goal of this work was to explore the influence of insulin and ascorbic acid and extracellular matrix (ECM) alignment on the recellularization of decellularized engineered tissue by human mesenchymal stem cells (hMSCs)....
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