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Article

Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis

26 Dec 2014

Abstract excerpt

OBJECTIVE: Identify gene changes in articular cartilage of the medial tibial plateau (MTP) at 2, 4 and 8 weeks after destabilisation of the medial meniscus (DMM) in mice. Compare our data with previously published datasets to ascertain dysregulated pathways and genes in osteoarthritis (OA). DESIGN: RNA was extracted from the ipsilateral and contralateral MTP cartilage, amplified, labelled and hybridized on...

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PMID: 25545425
DOI: 10.1016/j.joca.2014.12.014

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