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Article

Effect of genotype imputation on genome-enabled prediction of complex traits: an empirical study with mice data.

BMC genetics - 29 Dec 2014

Felipe Vivian P S, Okut Hayrettin, Gianola Daniel, Silva Martinho A, Rosa Guilherme J M

Abstract excerpt

BACKGROUND: Genotype imputation is an important tool for whole-genome prediction as it allows cost reduction of individual genotyping. However, benefits of genotype imputation have been evaluated mostly for linear additive genetic models. In this study we investigated the impact of employing imputed genotypes when using more elaborated models of phenotype prediction. Our hypothesis was that such models would be...

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Body Mass Index
Genetic Association Studies
Genome
Genomics
Genotype

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PMID: 25544265
DOI: 10.1186/s12863-014-0149-9
PMCID: PMC4333171

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