Enterolignan-producing phenotypes are associated with increased gut microbial diversity and altered composition in premenopausal women in the United States.

doi:10.1158/1055-9965.EPI-14-0262

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Enterolignan-producing phenotypes are associated with increased gut microbial diversity and altered composition in premenopausal women in the United States.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2015

Hullar Meredith A J, Lancaster Samuel M, Li Fei, Tseng Elizabeth, Beer Karlyn, Atkinson Charlotte, Wähälä Kristiina, Copeland Wade K, Randolph Timothy W, Newton Katherine M, Lampe Johanna W

Abstract excerpt

BACKGROUND: Lignans in plant foods are metabolized by gut bacteria to the enterolignans, enterodiol (END) and enterolactone (ENL). Enterolignans have biologic activities important to the prevention of cancer and chronic diseases. We examined the composition of the gut microbial community (GMC) as a contributor to human enterolignan exposure. METHODS: We evaluated the association between the GMC in stool, urinary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 4-Butyrolactone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastrointestinal Tract

Share to IMPACT gene

Share to Microbiota

Share to Phenotype

Share to Phytoestrogen effects and research

Share to Premenopause

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 25542830
DOI: 10.1158/1055-9965.EPI-14-0262
PMCID: PMC4392386

Genes

IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enterolignan-producing phenotypes are associated with increased gut microbial diversity and altered composition in premenopausal women in the United States.PMID 25542830Read ↗

Identification of Human Gut Microbiome Associated with Enterolignan ProductionSemantic proximity Read ↗

Enterolignan Production in a Flaxseed Intervention Study in Postmenopausal US Women of African Ancestry and European AncestrySemantic proximity Read ↗

Impact of lignans in oilseed mix on gut microbiome composition and enterolignan production in younger healthy and premenopausal women: an in vitro pilot studySemantic proximity Read ↗

Lignans and Gut Microbiota: An Interplay Revealing Potential Health ImplicationsSemantic proximity Read ↗

Intestinal Bacterial Communities That Produce Active Estrogen-Like Compounds Enterodiol and Enterolactone in HumansSemantic proximity Read ↗

Personalized Nutrition Using Microbial Metabolite Phenotype to Stratify Participants and Non-Invasive Host Exfoliomics Reveal the Effects of Flaxseed Lignan Supplementation in a Placebo-Controlled Crossover Trial.Semantic proximity Read ↗

Impact of lignans in oilseed mix on gut microbiome composition and enterolignan production in younger healthy and premenopausal women: an in vitro pilot studySemantic proximity Read ↗

Unveiling metabotype clustering in resveratrol, daidzein, and ellagic acid metabolism: Prevalence, associated gut microbiomes, and their distinctive microbial networksSemantic proximity Read ↗

Production of enterodiol from defatted flaxseeds through biotransformation by human intestinal bacteriaSemantic proximity Read ↗

Phylogeny of human intestinal bacteria that activate the dietary lignan secoisolariciresinol diglucosideSemantic proximity Read ↗

Metabolism of isoflavones, lignans and prenylflavonoids by intestinal bacteria: producer phenotyping and relation with intestinal community.Semantic proximity Read ↗

The Genetic Basis for the Cooperative Bioactivation of Plant Lignans by a Human Gut Bacterial ConsortiumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.