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Article

Association of Shorter Leukocyte Telomere Repeat Length With Dementia and Mortality

17 Jul 2012

Abstract excerpt

BACKGROUND: Shortening of chromosomal telomeres is a consequence of cell division and is a biological factor related to cellular aging and potentially to more rapid organismal biological aging. OBJECTIVE: To determine whether shorter telomere length (TL), as measured in human blood samples, is associated with the development of Alzheimer disease and mortality. DESIGN: We studied available stored leukocyte DNA...

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Identifiers

PMID: 22825311
DOI: 10.1001/archneurol.2012.1541

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