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Possible association of the BRCA2 gene C5972T variant with gastric cancer: a study on Polish population.

Polskie Archiwum Medycyny Wewnetrznej - 1 Jan 2015

Ławniczak Małgorzata, Jakubowska Anna, Białek Andrzej, Karpińska-Kaczmarczyk Katarzyna, Lubiński Jan, Starzyńska Teresa

Abstract excerpt

INTRODUCTION: Gastric cancer (GC) belongs to a group of cancers linked to BRCA2 gene mutations and observed in patients with a family history of breast and ovarian cancers. A common variant allele (C5972T) observed in the BRCA2 gene in the Polish population is associated with an increased risk of breast cancer. OBJECTIVES: The objective of the study was to assess a relationship between the BRCA2 C5972T variant...

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Identifiers

PMID: 25533971
DOI: 10.20452/pamw.2642

Genes

BRCA2

Variants

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