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Article

Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes.

Circulation - 10 Feb 2015

Yao Chen, Chen Brian H, Joehanes Roby, Otlu Burcak, Zhang Xiaoling, Liu Chunyu, Huan Tianxiao, Tastan Oznur, Cupples L Adrienne, Meigs James B, Fox Caroline S, Freedman Jane E, Courchesne Paul, O'Donnell Christopher J, Munson Peter J, Keles Sunduz, Levy Daniel

Abstract excerpt

BACKGROUND: Cardiovascular disease (CVD) reflects a highly coordinated complex of traits. Although genome-wide association studies have reported numerous single nucleotide polymorphisms (SNPs) to be associated with CVD, the role of most of these variants in disease processes remains unknown. METH...

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Identifiers

PMID: 25533967
DOI: 10.1161/CIRCULATIONAHA.114.010696
PMCID: PMC4369387

Genes

LDLR
PCSK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25533967-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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