Article
Genetic polymorphisms influence the ovarian response to rFSH stimulation in patients undergoing in vitro fertilization programs with ICSI.
PloS one - 1 Jan 2012
Boudjenah Radia, Molina-Gomes Denise, Torre Antoine, Bergere Marianne, Bailly Marc, Boitrelle Florence, Taieb Stéphane, Wainer Robert, Benahmed Mohamed, de Mazancourt Philippe, Selva Jacqueline, Vialard François
Abstract excerpt
INTRODUCTION: Obtaining an adequate number of high-quality oocytes is a major challenge in controlled ovarian hyperstimulation (COH). To date, a range of hormonal and clinical parameters have been used to optimize COH but none have significant predictive value. This variability could be due to the genetic predispositions of single-nucleotide polymorphisms (SNPs). Here, we assessed the individual and combined...
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