Article
The innate immune system and inflammatory bowel disease.
Scandinavian journal of gastroenterology - 1 Jan 2015
Davies Julie M, Abreu Maria T
Abstract excerpt
The innate immune system is a key factor in understanding the pathogenesis of inflammatory bowel disease (IBD) and in the hopes of improving its treatment. NOD2, a pattern recognition receptor, was one of the first major susceptibility genes identified in Crohn's disease (CD). This discovery has been followed by genome-wide association studies that have identified other genes involved in innate immune responses....
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