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Article

Subgenomic promoter recognition by the norovirus RNA-dependent RNA polymerases.

Nucleic acids research - 1 Jan 2015

Lin Xiaoyan, Thorne Lucy, Jin Zhinan, Hammad Loubna A, Li Serena, Deval Jerome, Goodfellow Ian G, Kao C Cheng

Abstract excerpt

The replication enzyme of RNA viruses must preferentially recognize their RNAs in an environment that contains an abundance of cellular RNAs. The factors responsible for specific RNA recognition are not well understood, in part because viral RNA synthesis takes place within enzyme complexes associated with modified cellular membrane compartments. Recombinant RNA-dependent RNA polymerases (RdRps) from the human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

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Identifiers

PMID: 25520198
DOI: 10.1093/nar/gku1292
PMCID: PMC4288183

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