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Article

In vivo evaluation of mutant selection window of cefquinome against Escherichia coli in piglet tissue-cage model.

BMC veterinary research - 16 Dec 2014

Zhang Bingxu, Gu Xiaoyan, Li Yafei, Li Xiaohong, Gu Mengxiao, Zhang Nan, Shen Xiangguang, Ding Huanzhong

Abstract excerpt

BACKGROUND: The resistance of cephalosporins is significantly serious in veterinary clinic. In order to inhibit the bacterial resistance production, the mutant selection window (MSW) hypothesis with Escherichia coli (E. coli) ATCC 25922 exposed to cefquinome in an animal tissue-cage model was investigated. RESULTS: Localized infection with E. coli was established in piglets, and the infected animals were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25511985
DOI: 10.1186/s12917-014-0297-1
PMCID: PMC4279896

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