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Article

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

24 May 2009

Abstract excerpt

Candida species are the most common cause of opportunistic fungal infection worldwide. Here we report the genome sequences of six Candida species and compare these and related pathogens and non-pathogens. There are significant expansions of cell wall, secreted and transporter gene families in pathogenic species, suggesting adaptations associated with virulence. Large genomic tracts are homozygous in three diploid...

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PMID: 19465905
DOI: 10.1038/nature08064

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