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Article

Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease.

PLoS genetics - 1 Dec 2014

Ganna Andrea, Salihovic Samira, Sundström Johan, Broeckling Corey D, Hedman Asa K, Magnusson Patrik K E, Pedersen Nancy L, Larsson Anders, Siegbahn Agneta, Zilmer Mihkel, Prenni Jessica, Arnlöv Johan, Lind Lars, Fall Tove, Ingelsson Erik

Abstract excerpt

Analyses of circulating metabolites in large prospective epidemiological studies could lead to improved prediction and better biological understanding of coronary heart disease (CHD). We performed a mass spectrometry-based non-targeted metabolomics study for association with incident CHD events in 1,028 individuals (131 events; 10 y. median follow-up) with validation in 1,670 individuals (282 events; 3.9 y....

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PMID: 25502724
DOI: 10.1371/journal.pgen.1004801
PMCID: PMC4263376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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