Article
Reduced ex vivo stimulated IL-6 response in infants randomized to fish oil from 9 to 18 months, especially among PPARG2 and COX2 wild types.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Mar 2015
Harsløf Laurine B S, Damsgaard Camilla T, Andersen Anders D, Aakjær Ditte L, Michaelsen Kim F, Hellgren Lars I, Frøkiær Hanne, Vogel Ulla, Lauritzen Lotte
Abstract excerpt
We investigated whether n-3 LCPUFA affected immune function in late infancy and explored effect-modification by single nucleotide polymorphisms (SNPs) and links to intestinal microbiota. Infants (n=105) were randomized to fish oil (FO, 1.2g/d n-3 LCPUFA) or sunflower oil (SO)-supplements from age 9-18 months. Immune function was assessed by ex vivo cytokine production in stimulated blood and plasma immunoglobulin...
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