Article
Incidence of dementia in relation to genetic variants at PITX2, ZFHX3, and ApoE ε4 in atrial fibrillation patients.
Pacing and clinical electrophysiology : PACE - 1 Feb 2015
Rollo Jeffrey, Knight Stacey, May Heidi T, Anderson Jeffrey L, Muhlestein Joseph B, Bunch T Jared, Carlquist John
Abstract excerpt
INTRODUCTION: Mechanisms underlying atrial fibrillation (AF) and dementia are unknown. Some genetic risk factors convey risk for AF and cerebral ischemic events. These markers may identify AF patients at risk for dementia either directly or through a gene-gene interaction with the ApoE ε4 variant, a known marker of dementia risk. METHODS: Caucasian patients with AF and a subsequent dementia diagnosis (n = 112)...
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