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Article

Phenotyping of Chronic Obstructive Pulmonary Disease Based on the Integration of Metabolomes and Clinical Characteristics.

International journal of molecular sciences - 27 Feb 2018

Kilk Kalle, Aug Argo, Ottas Aigar, Soomets Ursel, Altraja Siiri, Altraja Alan

Abstract excerpt

Apart from the refined management-oriented clinical stratification of chronic obstructive pulmonary disease (COPD), the molecular pathologies behind this highly prevalent disease have remained obscure. The aim of this study was the characterization of patients with COPD, based on the metabolomic profiling of peripheral blood and exhaled breath condensate (EBC) within the context of defined clinical and...

Topics

Adult
Aged
Biomarkers
Case-Control Studies
Cluster Analysis
Female
Humans
Male
Metabolome
Metabolomics
Middle Aged
Models, Statistical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Pulmonary Disease, Chronic Obstructive

Respiratory Function Tests

Risk Factors

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29495451
DOI: 10.3390/ijms19030666
PMCID: PMC5877527

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-29495451-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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