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Frequent detection of antiretroviral drug resistance in HIV-1-infected orphaned children followed at a donor-funded rural pediatric clinic in Dodoma, Tanzania.

AIDS research and human retroviruses - 1 Apr 2015

Meini Genny, Balestrieri Maddalena, Cianchino Sergio, Tacconi Danilo, Rossi de Gasperis Marco, Concato Carlo, Vicenti Ilaria, Rosi Andrea, Saladini Francesco, Callea Francesco, Zazzi Maurizio

Abstract excerpt

A total of 81 HIV-1 protease (PR) and reverse transcriptase (RT) sequences were obtained from 46 drug-naive and 35 pretreated individual HIV-1-infected orphaned children followed at a donor-funded rural pediatric clinic in Dodoma, Tanzania. PR and RT sequencing was performed by home-brew technology on 70 plasma samples and 11 dried blood spot specimens. Nucleoside RT inhibitor (NRTI) resistance mutations were...

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PMID: 25492218
DOI: 10.1089/AID.2014.0251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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