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Article

Breast cancer genetic risk profile is differentially associated with interval and screen-detected breast cancers.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Mar 2015

Li J, Holm J, Bergh J, Eriksson M, Darabi H, Lindström L S, Törnberg S, Hall P, Czene K

Abstract excerpt

BACKGROUND: Polygenic risk profiles computed from multiple common susceptibility alleles for breast cancer have been shown to identify women at different levels of breast cancer risk. We evaluated whether this genetic risk stratification can also be applied to discriminate between screen-detected and interval cancers, which are usually associated with clinicopathological and survival differences. PATIENTS AND...

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PMID: 25488685
DOI: 10.1093/annonc/mdu565

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