Article
Role of long non-coding RNA in drug resistance in non-small cell lung cancer.
Thoracic cancer - 1 Jul 2018
Wang Leirong, Ma Leina, Xu Fei, Zhai Wenxin, Dong Shenghua, Yin Ling, Liu Jia, Yu Zhuang
Abstract excerpt
Lung cancer is the leading cause of cancer-associated death, and non-small cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases. Many drugs have been used to treat NSCLC in order to improve patient prognosis. Platinum-based chemotherapy is the first-line treatment for locally advanced or metastatic patients. For patients with activating EGFR mutations, tyrosine kinase inhibitors are the best...
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