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Identification of a lineage specific zinc responsive genomic island in Mycobacterium avium ssp. paratuberculosis

1 Dec 2014

Abstract excerpt

BACKGROUND: Maintenance of metal homeostasis is crucial in bacterial pathogenicity as metal starvation is the most important mechanism in the nutritional immunity strategy of host cells. Thus, pathogenic bacteria have evolved sensitive metal scavenging systems to overcome this particular host defence mechanism. The ruminant pathogen Mycobacterium avium ssp. paratuberculosis (MAP) displays a unique gut tropism and...

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PMID: 25481572
DOI: 10.1186/1471-2164-15-1076

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