Article
RANK rs1805034 T>C Polymorphism Is Associated with Susceptibility to Gastric Cardia Adenocarcinoma in a Chinese Population.
Oncology research and treatment - 1 Jan 2015
Zhang Wen-Bo, Gu Hai-Yong, Shi Yi-Jun, Shao Ai-Zhong, Chen Suo-Cheng, Yin Jun, Jiang Peng-Cheng
Abstract excerpt
BACKGROUND: Gastric cardia adenocarcinoma (GCA) is a common malignant tumor of the digestive tract with a high incidence in China. Genetic factors such as single nucleotide polymorphisms (SNPs) may contribute to the carcinogenesis of GCA. METHODS: We conducted a hospital-based case-control study to evaluate the genetic association of functional SNPs with susceptibility to GCA development. A total of 330 GCA cases...
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