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Article

Mitochondrial dysfunction by pro-oxidant vanadium: ex vivo assessment of individual susceptibility.

Environmental toxicology and pharmacology - 1 Jan 2015

Visalli Giuseppa, Bertuccio Maria Paola, Picerno Isa, Spataro Pasquale, Di Pietro Angela

Abstract excerpt

The aim was to assess the individual susceptibility to mitochondrial impairment induced by ex vivo exposure to vanadium, an airborne pro-oxidant pollutant. In lymphocyte cultures V(IV)-treated of forty-five healthy subjects, we evaluated the mitochondrial transmembrane potential (Δψm) and the H2O2 in comparison to background values. As variables, we included both lifestyle factors and genetic polymorphisms (GSTM1...

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Source

Identifiers

PMID: 25473821
DOI: 10.1016/j.etap.2014.11.008

Genes

GSTM1
GSTT1
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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