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Article

Biomechanics and gene expression in abdominal aortic aneurysm.

Journal of vascular surgery - 1 Dec 2014

Reeps Christian, Kehl Sebastian, Tanios Fadwa, Biehler Jonas, Pelisek Jaroslav, Wall Wolfgang A, Eckstein Hans-Henning, Gee Michael W

Abstract excerpt

OBJECTIVE: The aim of the study was to detect inter-relations between the mechanical conditions and material properties of abdominal aortic aneurysm (AAA) wall and the underlying local gene expression of destabilizing inflammatory, proteolytic, and structural factors. METHODS: During open surgery, 51 tissue samples from 31 AAA patients were harvested. Gene expression of collagen types I and III, inflammatory...

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Share to Aorta, Abdominal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Stress, Mechanical

Share to Tomography, X-Ray Computed

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Source

Identifiers

PMID: 25454106
DOI: 10.1016/j.jvs.2014.08.076

Genes

MSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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