Article
Validation of the immunochromatographic strip for α-thalassemia screening: a multicenter study.
Translational research : the journal of laboratory and clinical medicine - 1 Jun 2015
Winichagoon Pranee, Kumpan Pornnapa, Holmes Paula, Finlayson Jill, Newbound Christopher, Kabral Arnold, Li Benjamin, Nuinoon Manit, Fawcett Terry, Tayapiwatana Chatchai, Kasinrerk Watchara, Fucharoen Suthat
Abstract excerpt
α(0)-Thalassemia occurs from a deletion of 2 linked α-globin genes and interaction of these defective genes leads to hemoglobin (Hb) Bart's hydrops fetalis, the most severe and lethal thalassemia syndrome. Identification of α(0)-thalassemia carriers is thus essential for the prevention and control program. An immunochromatographic (IC) strip test was developed for rapid screening of α(0)-thalassemia by testing...
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