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Article

Connexins, gap junctions and peripheral neuropathy.

Neuroscience letters - 2 Jun 2015

Kleopa Kleopas A, Sargiannidou Irene

Abstract excerpt

Gap junctions (GJs) have emerged as an important molecular component of peripheral myelinated fibers following the discovery of mutations affecting the GJ protein connexin32 (Cx32) in patients with the X-linked Charcot-Marie-Tooth neuropathy (CMT1X). CMT1X is the second most common CMT form and is caused by over 400 different mutations in the GJB1 gene encoding Cx32. In peripheral nerves, Cx32 is expressed by...

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Source

Identifiers

PMID: 25449862
DOI: 10.1016/j.neulet.2014.10.033

Genes

GJB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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