Article
Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer.
Cancer letters - 1 Feb 2015
Hao Chuncheng, Wang Li, Peng Shaohua, Cao Mengru, Li Hongyu, Hu Jing, Huang Xiao, Liu Wei, Zhang Hui, Wu Shuhong, Pataer Apar, Heymach John V, Eterovic Agda Karina, Zhang Qingxiu, Shaw Kenna R, Chen Ken, Futreal Andrew, Wang Michael, Hofstetter Wayne, Mehran Reza, Rice David, Roth Jack A, Sepesi Boris, Swisher Stephen G, Vaporciyan Ara, Walsh Garrett L, Johnson Faye M, Fang Bingliang
Abstract excerpt
Molecular annotated patient-derived xenograft (PDX) models are useful for the preclinical investigation of anticancer drugs and individualized anticancer therapy. We established 23 PDXs from 88 surgical specimens of lung cancer patients and determined gene mutations in these PDXs and their paired...
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