Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The accuracy, feasibility and challenges of sequencing short tandem repeats using next-generation sequencing platforms.

PloS one - 1 Jan 2014

Zavodna Monika, Bagshaw Andrew, Brauning Rudiger, Gemmell Neil J

Abstract excerpt

To date we have little knowledge of how accurate next-generation sequencing (NGS) technologies are in sequencing repetitive sequences beyond known limitations to accurately sequence homopolymers. Only a handful of previous reports have evaluated the potential of NGS for sequencing short tandem repeats (microsatellites) and no empirical study has compared and evaluated the performance of more than one NGS platform...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Genetic
Share to DNA, Fungal
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Microsatellite Repeats

Share to Saccharomyces cerevisiae

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 25436869
DOI: 10.1371/journal.pone.0113862
PMCID: PMC4250034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The accuracy, feasibility and challenges of sequencing short tandem repeats using next-generation sequencing platforms.PMID 25436869Read ↗

Sequencing technologies and tools for short tandem repeat variation detection.Semantic proximity Read ↗

Analysis of Tandem Repeats in Short-Read Sequencing Data: From Genotyping Known Pathogenic Repeats to Discovering Novel Expansions.Semantic proximity Read ↗

Recent advances in the detection of repeat expansions with short-read next-generation sequencingSemantic proximity Read ↗

Accuracy of short tandem repeats genotyping tools in whole exome sequencing dataSemantic proximity Read ↗

Accuracy of short tandem repeats genotyping tools in whole exome sequencing dataSemantic proximity Read ↗

Critical assessment of bioinformatics methods for the characterization of pathological repeat expansions with single-molecule sequencing data.Semantic proximity Read ↗

The effects of transcription and recombination on mutational dynamics of short tandem repeats.Semantic proximity Read ↗

Read-level genotyping of short tandem repeats using long reads and single-nucleotide variation with STRkit.Semantic proximity Read ↗

Profiling short tandem repeats from short reads.Semantic proximity Read ↗

Inferring short tandem repeat variation from paired-end short reads.Semantic proximity Read ↗

STRkit: precise, read-level genotyping of short tandem repeats using long reads and single-nucleotide variationSemantic proximity Read ↗

CRISPR-Cas9-targeted fragmentation and selective sequencing enable massively parallel microsatellite analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.