Article

Recent advances in the detection of repeat expansions with short-read next-generation sequencing

2018-06-13

Abstract excerpt

Short tandem repeats (STRs), also known as microsatellites, are commonly defined as consisting of tandemly repeated nucleotide motifs of 2–6 base pairs in length. STRs appear throughout the human genome, and about 239,000 are documented in the Simple Repeats Track available from the UCSC (University of California, Santa Cruz) genome browser. STRs vary in size, producing highly polymorphic markers commonly used as...

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Literature Corpus work: 832b5731-7381-5a44-ac4c-176782b1b04d
DOI: 10.12688/f1000research.13980.1

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