Article

Minimizing time in culture: A prototypic autologous manufacturing workflow for monoclonal iPSC lines within seven weeks

2026-08-10

Abstract excerpt

Induced pluripotent stem cells (iPSCs) hold great promise for both allogeneic and autologous cellular therapies. However, broad application and clinical translation is hindered by fragmented, complex and time-intensive workflows, resulting in high manufacturing costs, poor standardization and increased risk of genomic aberrations in derived iPSCs. In this study we developed a standardizable, automatable and time-...

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Literature Corpus work: a5e10d7b-ad2a-5545-8121-380f00babc31
DOI: 10.64898/2026.08.04.741960

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