Article
Exome sequencing identifies novel ApoB loss-of-function mutations causing hypobetalipoproteinemia in type 1 diabetes.
Acta diabetologica - 1 Jun 2015
Gao Feng, Luo Hao, Fu Zhiyao, Zhang Chun-Ting, Zhang Ren
Abstract excerpt
AIM: Diabetic patients commonly suffer from disturbances in production and clearance of plasma lipoproteins, known as diabetic dyslipidemia, resulting in an increased risk of coronary heart disease. The study aimed to examine the cause of hypobetalipoproteinemia in two patients with type 1 diabetes. METHODS: The Diabetes Control and Complications Trial (DCCT) is a study demonstrating that intensive blood glucose...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
