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Article

Associations of MTHFR C677T and MTRR A66G gene polymorphisms with metabolic syndrome: a case-control study in Northern China.

International journal of molecular sciences - 25 Nov 2014

Yang Boyi, Fan Shujun, Zhi Xueyuan, Wang Da, Li Yongfang, Wang Yinuo, Wang Yanxun, Wei Jian, Zheng Quanmei, Sun Guifan

Abstract excerpt

Prior evidence indicates that homocysteine plays a role in the development of metabolic syndrome (MetS). Methylenetetrahydrofolate reductase (MTHFR) C677T and methionine synthase reductase (MTRR) A66G polymorphisms are common genetic determinants of homocysteine levels. To investigate the associations of the MTHFR C677T and MTRR A66G polymorphisms with MetS, 692 Chinese Han subjects with MetS and 878 controls...

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Source

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Identifiers

PMID: 25429430
DOI: 10.3390/ijms151221687
PMCID: PMC4284672

Genes

MTHFR
MTRR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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