Article
Monoallelic expression of the human FOXP2 speech gene.
Proceedings of the National Academy of Sciences of the United States of America - 2 Jun 2015
Adegbola Abidemi A, Cox Gerald F, Bradshaw Elizabeth M, Hafler David A, Gimelbrant Alexander, Chess Andrew
Abstract excerpt
The recent descriptions of widespread random monoallelic expression (RMAE) of genes distributed throughout the autosomal genome indicate that there are more genes subject to RMAE on autosomes than the number of genes on the X chromosome where X-inactivation dictates RMAE of X-linked genes. Several of the autosomal genes that undergo RMAE have independently been implicated in human Mendelian disorders. Thus,...
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