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Article

MiRNA-1/133a Clusters Regulate Adrenergic Control of Cardiac Repolarization

21 Nov 2014

Abstract excerpt

The electrical properties of the heart are primarily determined by the activity of ion channels and the activity of these molecules is permanently modulated and adjusted to the physiological needs by adrenergic signaling. miRNAs are known to control the expression of many proteins and to fulfill distinct functions in the mammalian heart, though the in vivo effects of miRNAs on the electrical activity of the heart...

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PMID: 25415383
DOI: 10.1371/journal.pone.0113449

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