Article
Short duplication within the RHCE gene associated with an in cis deleted RHD causing a Rhnull amorph phenotype in an immunized pregnant woman with anti-Rh29.
Transfusion - 1 Jun 2015
Silvy Monique, Beley Sophie, Peyrard Thierry, Ouchari Mouna, Abdelkefi Saadia, Jemni Yacoub Saloua, Chiaroni Jacques, Bailly Pascal
Abstract excerpt
BACKGROUND: The rare amorph Rhnull phenotype is caused by silent alleles at the RH locus and usually arises in consanguineous families. To date, only five molecular backgrounds have been identified in five unrelated families. Subjects with Rhnull red blood cells (RBCs) readily produce alloantibodies to high-prevalence Rh antigens. STUDY DESIGN AND METHODS: RBCs from a pregnant woman (G5P3) from Libya, with a...
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