Molecular defects of the RHCE gene in Rh-deficient individuals of the amorph type.

Article

Molecular defects of the RHCE gene in Rh-deficient individuals of the amorph type.

Blood - 15 Jul 1998

Chérif-Zahar B, Matassi G, Raynal V, Gane P, Mempel W, Perez C, Cartron J P

Abstract excerpt

The deficiency of Rh proteins on the red blood cells from individuals of the Rhnull amorph type may be the result of homozygosity for a silent allele at the RH locus. This phenotype is also associated with the lack or reduced expression of glycoproteins (Rh50, CD47, LW, and glycophorin B), which...

Topics

Alleles
Amino Acid Sequence
Blood Proteins
Glycoproteins
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Rh-Hr Blood-Group System

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