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Article

Deletion Mutants of Schmallenberg Virus Are Avirulent and Protect from Virus Challenge

20 Nov 2014

Abstract excerpt

UNLABELLED: Since its emergence, Schmallenberg virus (SBV), a novel insect-transmitted orthobunyavirus which predominantly infects ruminants, has caused a large epidemic in European livestock. Newly developed inactivated vaccines are available, but highly efficacious and safe live vaccines are still not available. Here, the properties of novel recombinant SBV mutants lacking the nonstructural protein NSs...

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PMID: 25410877
DOI: 10.1128/jvi.02729-14

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