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Vaccine development against Schmallenberg virus: from classical inactivated to modified-live to scaffold particle vaccines

17 Aug 2022

Abstract excerpt

BACKGROUND: Subsequent to its first detection in 2011, the insect-transmitted bunyavirus Schmallenberg virus (SBV; genus Orthobunyavirus) caused a large-scale epizootic of fetal malformation in the European ruminant population. By now, SBV established an enzootic status in Central Europe with regular wave-like re-emergence, which has prompted intensive research efforts in order to elucidate the pathogenesis and...

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PMID: 35978443
DOI: 10.1186/s42522-022-00069-8

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