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Article

Interactions between ultraviolet light and MC1R and OCA2 variants are determinants of childhood nevus and freckle phenotypes.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2014

Barón Anna E, Asdigian Nancy L, Gonzalez Victoria, Aalborg Jenny, Terzian Tamara, Stiegmann Regan A, Torchia Enrique C, Berwick Marianne, Dellavalle Robert P, Morelli Joseph G, Mokrohisky Stefan T, Crane Lori A, Box Neil F

Abstract excerpt

BACKGROUND: Melanocytic nevi (moles) and freckles are well known biomarkers of melanoma risk, and they are influenced by similar UV light exposures and genetic susceptibilities to those that increase melanoma risk. Nevertheless, the selective interactions between UV exposures and nevus and freckl...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25410285
DOI: 10.1158/1055-9965.EPI-14-0633
PMCID: PMC4257874

Genes

OCA2
HERC2
IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25410285-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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