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Article

The atypical response regulator HP1021 controls formation of the Helicobacter pylori replication initiation complex.

Molecular microbiology - 1 Jan 2015

Donczew Rafał, Makowski Łukasz, Jaworski Paweł, Bezulska Martyna, Nowaczyk Małgorzata, Zakrzewska-Czerwińska Jolanta, Zawilak-Pawlik Anna

Abstract excerpt

The replication of a bacterial chromosome is initiated by the DnaA protein, which binds to the specific chromosomal region oriC and unwinds duplex DNA within the DNA-unwinding element (DUE). The initiation is tightly regulated by many factors, which control either DnaA or oriC activity and ensure that the chromosome is duplicated only when the conditions favor the survival of daughter cells. The factors...

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PMID: 25402746
DOI: 10.1111/mmi.12866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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