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Article

A genetic variant of miR-148a binding site in the SCRN1 3'-UTR is associated with susceptibility and prognosis of gastric cancer.

Scientific reports - 17 Nov 2014

Song Peng, Zhu Haixia, Zhang Dong, Chu Haiyan, Wu Dongmei, Kang Meiyun, Wang Meilin, Gong Weida, Zhou Jianwei, Zhang Zhengdong, Zhao Qinghong

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in the 3'-untranslated regions targeted by putative mircoRNA can change its binding strength, affecting the susceptibility and prognosis of cancer. We aimed to investigate the associations between SNPs within miR-148a binding sites and gastric cancer (GC) risk and prognosis. Using bioinformatics tools, we selected two SNPs (SCRN1 rs6976789 and PDYN rs2235749) located in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to 3' Untranslated Regions
Share to Aged, 80 and over
Share to Binding Sites
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Source

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Identifiers

PMID: 25399950
DOI: 10.1038/srep07080
PMCID: PMC5382666

Genes

SCRN1
PDYN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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