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Article

Association between a PD-1 gene polymorphism and antisperm antibody-related infertility in Iranian men.

Journal of assisted reproduction and genetics - 1 Jan 2015

Zamani Mohammad Reza, Asbagh Firouzeh Akbari, Massoud Amir Hossein, Salmaninejad Arash, Massoud Ahmad, Rezaei Nima

Abstract excerpt

OBJECTIVE: Programmed cell death-1 (PD-1, Pdcd1), an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signalling by recruiting protein tyrosine phosphatase, SHP-2 upon interacting with either of two ligands, PD-L1 or PD-L2. This study investigates PD-1 gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Share to Protein Tyrosine Phosphatase, Non-Receptor Type 11

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Source

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Identifiers

PMID: 25399062
DOI: 10.1007/s10815-014-0371-4
PMCID: PMC4294861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-25399062-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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