Article
Differential β₂-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines.
Oncotarget - 30 Oct 2014
Gargiulo Lucía, Copsel Sabrina, Rivero Ezequiel M, Galés Céline, Sénard Jean-Michel, Lüthy Isabel A, Davio Carlos, Bruzzone Ariana
Abstract excerpt
Breast cancer is the most frequent malignancy in women. Several reports demonstrated that adrenergic receptors (ARs) are involved in breast cancer. Here we observed that epinephrine (Epi), an endogenous AR agonist, caused opposite effects in non-tumorigenic (MCF-10A and HBL-100) and tumor cells (...
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