Article
Cervical cancer-associated promoter polymorphism affects akna expression levels.
Genes and immunity - 1 Jan 2000
Martínez-Nava G A, Torres-Poveda K, Lagunas-Martínez A, Bahena-Román M, Zurita-Díaz M A, Ortíz-Flores E, García-Carrancá A, Madrid-Marina V, Burguete-García A I
Abstract excerpt
Cervical cancer (CC) is responsible for >260,000 deaths worldwide each year. Efforts are being focused on identifying genetic susceptibility factors, especially in genes related to the immune response. Akna has been proposed to be one of them, but data regarding its functional role in the disease is scarce. Supporting the notion of akna as a CC susceptibility gene, we found two polymorphisms associated with...
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